Rajinikanth

'Annaatthe' Kaalaiyaan

Keerthy Suresh

Thanga Meenakshi

Jagapati Babu

Udhav Palekar

Soori

Pachakili

Nayanthara

Pattamal

Meena

Mangayarkarasi

Khushboo

Angayarkanni

Bala

Arjun

Prakash Raj

Nattadurai

Abhimanyu Singh

Manoj Palekar

Vela Ramamoorthy

Kaalaiyan’s uncle

Pandiarajan

Angayarkanni’s husband

Livingston

Mangayarkarasi’s husband

Sathyan Sivakumar

Mangayarkarasi’s brother

Sathish

Angayarkanni’s brother

George Mariyan

Komberi Mookan

Redin Kingsley

Nattadurai's Brother In Law

Thavasi

Priest

Kabali Vishwanth

Arjai

Kulappulli Leela

Kaalaiyaan’s grandmother

Billy Murali

Manoj Palekar's Henchman

Brana